Oncology Press Releases

I spearheaded Oncology research writing at Impact Journals, managing social media, podcasts, and press releases. Led a team, raised web traffic by 39.8%, and resolved SEO challenges, expanding global impact. Presented at industry conferences and pioneered multimedia content for the #1 Oncology journal in the world from 2017-2021.

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I became an expert at plain languaging oncology-focused, peer-reviewed, open access research to bridge gaps between specialties in cancer research, oncology, and biomedical sciences. My work aimed to unite diverse fields and apply both basic and clinical science.

I covered research about all molecules, pathways, cellular functions, and tissues as potential targets not only for cancer but also for various diseases which fostered a holistic understanding of disease mechanisms.

Altered glucuronidation signifies castration resistance in prostate cancer

Importantly, the knockdown of UGDH in both LNCaP AD and CR cells dramatically sensitized these cells to enzalutamide

PEER-REVIEWED PUBLICATION | /SCIENTIFIC COMMUNITY/RESEARCH PROGRAMS/CANCER RESEARCH

16-Nov-2021

Risk of colorectal cancer from smoking and red/processed meat carcinogens

This Oncotarget study helps to better define the molecular effects of representative carcinogens from smoking and red/processed meat in normal colon epithelial cells and in the etiology of the MSI-H subtype of CRC

PEER-REVIEWED PUBLICATION | /SCIENTIFIC COMMUNITY/RESEARCH PROGRAMS/CANCER RESEARCH

16-Nov-2021

The antitumoral effects of chemerin

CMKLR1, also named ChemR23 or chemerin1, was the first receptor described for chemerin

PEER-REVIEWED PUBLICATION | /SCIENTIFIC COMMUNITY/RESEARCH PROGRAMS/CANCER RESEARCH

16-Nov-2021

High expression of Myosin 1g in pediatric acute lymphoblastic leukemia

Leukemia is the most common type of cancer in childhood, particularly affecting children under 15 years old, with a prevalence between the ages of 2 to 5 years

PEER-REVIEWED PUBLICATION | /HEALTH AND MEDICINE/MEDICAL SPECIALTIES/ONCOLOGY/CANCER PATIENTS

12-Nov-2021

Nanoparticle T cell engagers for the treatment of acute myeloid leukemia

This immunotherapeutic option has been shown to be successful for both solid and liquid tumors, but is mostly known for the treatment of hematological malignancies

PEER-REVIEWED PUBLICATION | /SCIENTIFIC COMMUNITY/RESEARCH PROGRAMS/CANCER RESEARCH

12-Nov-2021

Enhancing doxorubicin anti-tumor efficacy and ameliorating cardiotoxicity

Despite generally positive findings in regard to exercise and cancer outcomes, it remains unclear how to properly prescribe exercise

PEER-REVIEWED PUBLICATION | /SCIENTIFIC COMMUNITY/RESEARCH PROGRAMS/CANCER RESEARCH

10-Nov-2021

Hyperprogression of a mismatch repair-deficient colon cancer

One of the major obstacles in understanding the pathophysiology of HPD/HP is a lack of preclinical experimental in vivo models, making it difficult to study this phenomenon

PEER-REVIEWED PUBLICATION | /SCIENTIFIC COMMUNITY/RESEARCH PROGRAMS/CANCER RESEARCH

9-Nov-2021

Hypertension and medication after maxillofacial tumors radical surgery

The incidence of POD in the hypertension group was 41%, compared with 12% in the nonhypertension group

PEER-REVIEWED PUBLICATION | /SCIENTIFIC COMMUNITY/RESEARCH PROGRAMS/CLINICAL RESEARCH

8-Nov-2021

PD-L1 expression and MET gene amplification in non-small cell lung cancer

A positive correlation was found between MET gene amplification and PD-L1 expression and highly expressed in patients with NSCLC and no other actionable oncogenic driver

PEER-REVIEWED PUBLICATION | /SCIENTIFIC COMMUNITY/RESEARCH PROGRAMS/CANCER RESEARCH

5-Nov-2021

Enhancing anti-tumor activity in triple negative breast cancer

Patients with TNBC have poor prognosis with the worst disease-free and overall survival rates of all breast cancer types

PEER-REVIEWED PUBLICATION | /HEALTH AND MEDICINE/DISEASES AND DISORDERS/CANCER/BREAST CANCER

4-Nov-2021Oncotarget: Impact factor and citation metrics in phase III cancer trials

Trials that met their primary endpoint were more commonly published in journals with higher IF

PEER-REVIEWED PUBLICATION | /SCIENTIFIC COMMUNITY/RESEARCH PROGRAMS/CANCER RESEARCH

3-Nov-2021

Decreasing DNA repair and genomic instability

Remission induction chemotherapy including the nucleoside analog cytarabine and an anthracycline and/or other topoisomerase 2 inhibitor remains first-line therapy for AML

PEER-REVIEWED PUBLICATION | /SCIENTIFIC COMMUNITY/RESEARCH PROGRAMS/CLINICAL RESEARCH

2-Nov-2021

Inducing apoptosis in T-cell acute lymphoblastic leukemia

Dr. H. Daniel Lacorazza from The Baylor College of Medicine said, "Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, with more than 3,000 new cases diagnosed every year in the U.S."

PEER-REVIEWED PUBLICATION | /HEALTH AND MEDICINE/CLINICAL MEDICINE/MEDICAL TREATMENTS/CANCER TREATMENTS/CANCER MEDICATION

1-Nov-2021

The role of circulating miRNAs and CA19-9 in pancreatic cancer diagnosis

Plasma cell-free miRNAs have been pointed out as important future clinical biomarkers in different tumors

PEER-REVIEWED PUBLICATION | /SCIENTIFIC COMMUNITY/RESEARCH PROGRAMS/CANCER RESEARCH

13-Oct-2021

TP53 mutations determined by targeted NGS in breast cancer

This case-control study suggests that TP53 somatic mutations detected by next-generation sequencing are associated with an adverse prognosis in breast cancer

PEER-REVIEWED PUBLICATION | /SCIENTIFIC COMMUNITY/RESEARCH PROGRAMS/CANCER RESEARCH

12-Oct-2021

Integrating genomic profiling into clinical care: a nation-wide survey

Dr. Subotheni Thavaneswaran said, "Medical oncologists were among the first clinicians to integrate genomics into clinical care."

PEER-REVIEWED PUBLICATION | /SCIENTIFIC COMMUNITY/RESEARCH PROGRAMS/CANCER RESEARCH

12-Oct-2021

TAK1-inhibitors are cytotoxic for multiple myeloma cells

Their findings suggest that TAK1-inhibitors in combination with DNA-damaging agents represent a potential treatment strategy in MM patients

PEER-REVIEWED PUBLICATION | /HEALTH AND MEDICINE/CLINICAL MEDICINE/MEDICAL TREATMENTS/CANCER TREATMENTS

12-Oct-2021

Cytokinome screen of colon cancer cell responses to oncology drugs

There exists a degree of heterogeneity in the prognostic value of cytokines, with some showing opposing correlations in response to therapy across multiple tumor types

PEER-REVIEWED PUBLICATION | /LIFE SCIENCES/CELL BIOLOGY/CELLULAR PHYSIOLOGY/CELL RESPONSES

12-Oct-2021

Technology for the identification of MYC:TRRAP inhibitors

TRRAP could be required for efficient HAT activity because it enables the presentation of lysine tails by denaturing nucleosomes

PEER-REVIEWED PUBLICATION | /SCIENTIFIC COMMUNITY/RESEARCH PROGRAMS/CANCER RESEARCH

12-Oct-2021

Association of four genetic variants with colorectal cancer

Colorectal cancer (CRC) affects more than 1.9 million patients annually, and more than 935,000 die from the disease, which brings CRC third rank by incidence and second rank by mortality among other cancers

PEER-REVIEWED PUBLICATION | /SCIENTIFIC COMMUNITY/RESEARCH PROGRAMS/CANCER RESEARCH

12-Oct-2021

BRCA1 mRNA expression in breast and colorectal cancer

There is much interest in the field of cancer research regarding development of biomarkers to individualize treatment of existing therapies

PEER-REVIEWED PUBLICATION | /SCIENTIFIC COMMUNITY/RESEARCH PROGRAMS/CANCER RESEARCH

12-Oct-2021

The protective role of prolyl oligopeptidase inhibition in acute lung injury

The aim of the present study was to assess the beneficial outcomes of POP-inhibition in lung disease

PEER-REVIEWED PUBLICATION | /LIFE SCIENCES/ORGANISMAL BIOLOGY/ANATOMY/RESPIRATORY SYSTEM/LUNGS

11-Oct-2021

CRISPR/Cas9-directed epigenetic editing

Increasing number of studies report that proteins do not work in isolation but are part of a complex network of biomolecules, that may differ at various settings (e.g., different tumor types [1, 2] or stages of tumor progression.

PEER-REVIEWED PUBLICATION | /LIFE SCIENCES/CELL BIOLOGY/CELLS/CANCER CELLS

11-Oct-2021

miRNA expression in cirrhosis and liver cancer

Liver cancer despite its relatively low incidence rate with a geographically varied global burden is a fatal disease due to its high mortality rate: 5-year survival rate changes from 2% to 33% depending on the stage of the disease at the time of the diagnosis.

PEER-REVIEWED PUBLICATION | /SCIENTIFIC COMMUNITY/RESEARCH PROGRAMS/CANCER RESEARCH

11-Oct-2021

Scent test to screen for early-stage pancreatic cancer

Similar to sniffer dogs, the use of Caenorhabditis elegans has been introduced as a new strategy for detecting cancer-associated scents during cancer screening

PEER-REVIEWED PUBLICATION | /SCIENTIFIC COMMUNITY/RESEARCH PROGRAMS/CANCER RESEARCH

8-Oct-2021

Quantitative difference of oral pathogen with gastric cancer

Cancer is one of the major public health problems worldwide, and an estimated 19.3 million new cancer cases occurred in 2020

PEER-REVIEWED PUBLICATION | /SCIENTIFIC COMMUNITY/RESEARCH PROGRAMS/CANCER RESEARCH

6-Oct-2021

Epigenetic signatures differentiate uterine/soft tissue leiomyosarcoma

Epigenetic therapies may be promising candidates for managing sarcomas and other tumor types

PEER-REVIEWED PUBLICATION | /SCIENTIFIC COMMUNITY/RESEARCH PROGRAMS/CLINICAL RESEARCH

4-Oct-2021

Inhibiting thyroid cell proliferation by targeting signaling pathways

Thyroid cancer is the most prevalent endocrine cancer by constituting almost 93% of cancers associated to this system

PEER-REVIEWED PUBLICATION | /SCIENTIFIC COMMUNITY/RESEARCH PROGRAMS/CANCER RESEARCH

4-Oct-2021

High CD39 expression is associated with human bladder cancer

They investigated the proteic expression of CD39 and CD73 in patients who underwent surgery for the treatment of NMI and MI urothelial bladder carcinoma

PEER-REVIEWED PUBLICATION | /SCIENTIFIC COMMUNITY/RESEARCH PROGRAMS/CANCER RESEARCH

4-Oct-2021

Cell cycle arrest and anaphase catastrophe in malignant T-cells

The authors report that PTCL is characterized by an increased rate of chromosomal instability

PEER-REVIEWED PUBLICATION | /SCIENTIFIC COMMUNITY/RESEARCH PROGRAMS/CANCER RESEARCH

28-Sep-2021

Treating unresectable intrahepatic cholangiocarcinoma

Radioembolization of unresectable intrahepatic cholangiocarcinoma with ablative intent has a high response rate, promising survival, and is well tolerated

PEER-REVIEWED PUBLICATION | /SCIENTIFIC COMMUNITY/RESEARCH PROGRAMS/CANCER RESEARCH

28-Sep-2021

Low tumour-infiltrating lymphocyte density in glioblastoma

Glioblastoma, the most common and aggressive brain tumour occurring in adults, accounts for ~56% of newly diagnosed central nervous system (CNS) cancers in Australia

PEER-REVIEWED PUBLICATION | /SCIENTIFIC COMMUNITY/RESEARCH PROGRAMS/CANCER RESEARCH

28-Sep-2021

Tissue biodistribution and tumor targeting in preclinical multiple myeloma

The authors posit that DARA conjugated to DM1 via a non-cleavable linker will enhance the potency of the native DARA

PEER-REVIEWED PUBLICATION | /SCIENTIFIC COMMUNITY/RESEARCH PROGRAMS/CANCER RESEARCH

28-Sep-2021

Comparison of transcriptomic & cytokine responses in colorectal cancer

Together, the findings here contribute to the authors' understanding of the molecular bases of efficacy and toxicity of chemotherapeutic agents often used for treatment of GI cancer such as CRC

PEER-REVIEWED PUBLICATION | /SCIENTIFIC COMMUNITY/RESEARCH PROGRAMS/CANCER RESEARCH

28-Sep-2021

PBMCs generate TEM/TCM for adoptive cell therapy in multiple myeloma

MM cells are highly sensitive to the granule exocytosis pathway mediated by WT1-specific cytotoxic T lymphocytes

PEER-REVIEWED PUBLICATION | /SCIENTIFIC COMMUNITY/RESEARCH PROGRAMS/CANCER RESEARCH

28-Sep-2021

Distinct differences between molecular profiles of 3D and 2D cultured cells

The differential molecular phenotype of a NSCLC cell line membrane proteome grown in 2D- vs. 3D-culture is still missing

PEER-REVIEWED PUBLICATION | /SCIENTIFIC COMMUNITY/RESEARCH PROGRAMS/CANCER RESEARCH

28-Sep-2021

Telomere dysfunction and chromosome instability in cancer cells

These terpyridine platinum-derived G4 ligands are promising compounds for cancer treatment.

PEER-REVIEWED PUBLICATION | /SCIENTIFIC COMMUNITY/RESEARCH PROGRAMS/CANCER RESEARCH

6-Sep-2021

Epithelial-to-mesenchymal transition by association with NEAT1 lncRNA

Dr. Urmi Chatterji from The University of Calcutta said, "In the past few years, there has been a drastic rise in the incidence of head and neck cancers worldwide."

PEER-REVIEWED PUBLICATION | /SCIENTIFIC COMMUNITY/RESEARCH PROGRAMS/CANCER RESEARCH

3-Sep-2021

Exosomal markers expression and their significance in rectal adenocarcinoma

Dr. Moh'd Khushman from The O'Neal Comprehensive Cancer Center said in their Oncotarget Research Output, "Colorectal cancer (CRC) is a common disease."

PEER-REVIEWED PUBLICATION | /SCIENTIFIC COMMUNITY/RESEARCH PROGRAMS/CANCER RESEARCH

1-Sep-2021

RNA expression differences between Black and White Americans

The Oncotarget authors found fewer activated dendritic cells in the tumor and more CD8 T-cells in TAS of BA versus WA PCa patients

PEER-REVIEWED PUBLICATION | /HEALTH AND MEDICINE/MEDICAL SPECIALTIES/ONCOLOGY/CANCER GENETICS

30-Aug-2021

Predictors for risk of lymphovascular invasion in head and neck cancers

"Recurrent or metastatic head and neck cancer (HNSC) that includes tumors of oral cavity, paranasal sinuses, nasal cavity, pharynx, and larynx is associated with poor patient outcome, tumor aggressiveness and is characterized by early metastasis to the regional lymph nodes."

PEER-REVIEWED PUBLICATION | /SCIENTIFIC COMMUNITY/RESEARCH PROGRAMS/CANCER RESEARCH

30-Aug-2021

Biliary tract cancer by genome transcriptome analysis & Asian cancer knowledgebase

"Biliary tract cancer (BTC) or cholangiocarcinoma, which originates from bile duct epithelial cells (cholangiocytes), is a rare tumor worldwide."

PEER-REVIEWED PUBLICATION | /HEALTH AND MEDICINE/CLINICAL MEDICINE/MEDICAL TREATMENTS/CANCER TREATMENTS/CANCER MEDICATION

30-Aug-2021

Disabling the PI3K/Akt/mTOR survival pathway and inducing apoptosis

Combining SFN AZ significantly inhibits the PI3K/Akt/mTOR pathway and significantly reducing 5-HT secretion in carcinoid syndrome

PEER-REVIEWED PUBLICATION | /HEALTH AND MEDICINE/CLINICAL MEDICINE/MEDICAL TREATMENTS/CANCER TREATMENTS

27-Aug-2021

Esomeprazole enhances effect of ionizing radiation to improve tumor control

This Oncotarget Research Output indicates that esomeprazole sensitizes cancer cells to ionizing radiation, and is associated with upregulation of p21 to arrest cells in the G1 phase of the cell cycle.

PEER-REVIEWED PUBLICATION | /SCIENTIFIC COMMUNITY/RESEARCH PROGRAMS/CANCER RESEARCH

9-Aug-2021

Iron chelating properties in pediatric acute myeloid leukemia

This Oncotarget Research Output demonstrated that ELT improves cytarabine antineoplastic activity in pediatric AML cell lines

PEER-REVIEWED PUBLICATION | /SCIENTIFIC COMMUNITY/RESEARCH PROGRAMS/CANCER RESEARCH

9-Aug-2021

Appropriate body mass index cutoffs for type 2 diabetes in Xinjiang population

Type 2 diabetes (T2DM) is one of the most serious public health issues in the 21st century and is becoming increasingly prevalent worldwide

PEER-REVIEWED PUBLICATION | /HEALTH AND MEDICINE/HUMAN HEALTH/BIOMETRICS/BODY MASS INDEX

9-Aug-2021

Odds of breast cancer by molecular subtype: analysis of the MEND study

In 2018, there were over 2 million cases and 0.6 million deaths from breast cancer (BC), making it the most common cancer globally among women.

PEER-REVIEWED PUBLICATION | /HEALTH AND MEDICINE/DISEASES AND DISORDERS/CANCER/BREAST CANCER

9-Aug-2021

Response to neoadjuvant chemotherapy in locally advanced breast cancer

Pre-treatment T2-weighted MRI texture features can predict NAC response with reasonable accuracy.

PEER-REVIEWED PUBLICATION | /HEALTH AND MEDICINE/DISEASES AND DISORDERS/CANCER/BREAST CANCER

6-Aug-2021

Prokineticin-1 in colorectal cancer

PROK1 is a lymphangiogenic factor involved in the formation of new lymph vessels and lymph node metastasis in human colorectal cancer

PEER-REVIEWED PUBLICATION | /HEALTH AND MEDICINE/DISEASES AND DISORDERS/CANCER/COLORECTAL CANCER

4-Aug-2021

Oncogenic transformation of NIH/3T3 cells, a promising anti-cancer target

Anti-LAT1 monoclonal antibodies significantly inhibited in vitro cell proliferation and in vivo tumor growth of naLAT1/3T3 cells in nude mice, demonstrating LAT1 to be a promising anti-cancer target

PEER-REVIEWED PUBLICATION | /LIFE SCIENCES/CELL BIOLOGY/CELLS/CELL LINES

4-Aug-2021

A platform to control HNSCC recurrence following tumor resection

These Oncotarget data demonstrate that local delivery of tumor-specific T-cells is an efficient option to convert tumors that are unresponsive to checkpoint inhibitors to permit tumor cures.

PEER-REVIEWED PUBLICATION | /HEALTH AND MEDICINE/MEDICAL SPECIALTIES/IMMUNOLOGY/IMMUNE CELLS/LEUKOCYTES/LYMPHOCYTES/T LYMPHOCYTES

2-Aug-2021

DNA assay predicts treatment response in head and neck carcinoma

The authors developed and analytically validated a new droplet digital PCR -based assay for HPV16 circulating tumor DNA

PEER-REVIEWED PUBLICATION | /HEALTH AND MEDICINE/CLINICAL MEDICINE/MEDICAL TREATMENTS/CANCER TREATMENTS

2-Aug-2021

Replication-stress sensitivity in breast cancer cells

Taken together these Oncotarget findings show that the CTD and OD domains of mtp53 R273H play critical roles in mutant p53 GOF that pertain to processes associated with DNA replication.

PEER-REVIEWED PUBLICATION | /LIFE SCIENCES/BIOCHEMISTRY/PROTEIN FUNCTIONS/PROTEIN DOMAINS/DNA BINDING DOMAINS

26-Jul-2021

TERT and its binding protein: overexpression of GABPA/B in gliomas

This Oncotarget study confirms the upregulation of TERT in primary glioblastomas while all GABP proteins rise with the malignancy of the gliomas.

PEER-REVIEWED PUBLICATION | /LIFE SCIENCES/ORGANISMAL BIOLOGY/ANATOMY/TISSUE/NEOPLASMS/GLIOMAS

26-Jul-2021

Fgr and Numb in retinoic differentiation and G0 arrest of non-APL AML cells

In sum the Oncotarget data support a paradigm where signaling molecules bound to a Numb scaffold in a signalsome are activated by RA-induced Fgr expression

PEER-REVIEWED PUBLICATION | /LIFE SCIENCES/SIGNAL TRANSDUCTION/REGULATORY MECHANISMS/REGULATION BY PHOSPHORYLATION

23-Jul-2021

Subtypes of thymic epithelial tumors independent of WHO type

These Oncotarget results may reflect the unselected patient population enrolled in these studies, including no selection for WHO histologic subtype or molecular aberrations.

PEER-REVIEWED PUBLICATION | /LIFE SCIENCES/CELL BIOLOGY/CELLS/CELL LINES

21-Jul-2021

Biomechanics in response to drug in hypoxia by atomic force spectroscopy

These Oncotarget results show that a degree of chemotherapeutic drug effects on biomechanical and biophysical properties of cancer cells is distinguishable in normoxia and hypoxia`

PEER-REVIEWED PUBLICATION | /LIFE SCIENCES/CELL BIOLOGY/CELLS/CANCER CELLS/BREAST CANCER CELLS

19-Jul-2021

Cutaneous apocrine sweat gland carcinoma

Together these Oncotarget results describe the first ever CAC case with a BRCAness genetic background.

PEER-REVIEWED PUBLICATION | /LIFE SCIENCES/ORGANISMAL BIOLOGY/ANATOMY/INTEGUMENTARY SYSTEM/SKIN/SWEAT GLANDS

19-Jul-2021

Caspase-11 and AIM2 inflammasome involved in COPD and lung adenocarcinoma

The Oncotarget authors found that AIM2 inflammasome is at the crossroad between COPD and lung cancer in that its higher presence is correlated to lower survival rate of smoking COPD adenocarcinoma patients.

PEER-REVIEWED PUBLICATION | /HEALTH AND MEDICINE/DISEASES AND DISORDERS/RESPIRATORY DISORDERS/CHRONIC OBSTRUCTIVE PULMONARY DISEASE

19-Jul-2021

RAS reversion in colorectal cancer patients treated with bevacizumab

This Oncotarget finding might have potential therapeutic implications, as anti-EGFR could be reconsidered in primarily RAS mutant patients reverted to a wild-type status after bevacizumab exposure.

PEER-REVIEWED PUBLICATION | /LIFE SCIENCES/PHYSIOLOGY/PATHOPHYSIOLOGY/NEOPLASTIC PROCESSES/METASTASIS

16-Jul-2021

CEA as a blood-based biomarker in anal cancer

CEA is not associated with survival outcomes in SCCA, and is not a clinically relevant biomarker in this disease.

PEER-REVIEWED PUBLICATION | /HEALTH AND MEDICINE/CLINICAL MEDICINE/MEDICAL DIAGNOSIS/BIOMARKERS

14-Jul-2021

Inhibitory effects of Tomivosertib in acute myeloid leukemia

These Oncotarget findings demonstrate that Tomivosertib exhibits potent anti-leukemic properties on AML cells and support the development of clinical translational efforts involving the use of this drug.

PEER-REVIEWED PUBLICATION | /HEALTH AND MEDICINE/DISEASES AND DISORDERS/CANCER/LEUKEMIA/MYELOID LEUKEMIA

12-Jul-2021

Modulating Tau Post-translational modifications and cytoskeletal network

EGCG, a green tea polyphenol, as a modulator of in vitro methylglyoxal-induced Tau glycation and its impact on reducing advanced glycation end products in neuroblastoma cells.

PEER-REVIEWED PUBLICATION | /LIFE SCIENCES/CELL BIOLOGY/CELLS/NEURONS

12-Jul-2021

LAPAS1 is required for S phase progression and cell proliferation

They identify LAPAS1 as a novel E2F-regulated lncRNA that has a potential role in human cancer and regulates cell-cycle progression and cell proliferation

PEER-REVIEWED PUBLICATION | /LIFE SCIENCES/GENETICS/MOLECULAR GENETICS/GENETIC MATERIAL/RNA/NONCODING RNA/LONG NONCODING RNA

12-Jul-2021

Urine RNA reveal tumor markers for human bladder cancer

This Oncotarget work strongly suggests exploiting urine RNAs as diagnostic markers of bladder cancer and it suggests specific novel markers.

PEER-REVIEWED PUBLICATION | /LIFE SCIENCES/ORGANISMAL BIOLOGY/ANATOMY/BODY FLUIDS/URINE

9-Jul-2021

miRNA signatures from epidermal growth factor inhibitor patients

This Oncotarget study suggests that miR-21, miR-31 and miR-520e expression might be a treatment dependent marker for EGFRI induced skin rash.

PEER-REVIEWED PUBLICATION | /HEALTH AND MEDICINE/DISEASES AND DISORDERS/SKIN DISORDERS

7-Jul-2021

General anesthesia for pancreatic cancer surgery

The major finding of this Oncotarget study was perioperative tryptophan depletion and increased taurine synthesis.

PEER-REVIEWED PUBLICATION | /HEALTH AND MEDICINE/MEDICAL SPECIALTIES/ANESTHESIOLOGY/ANESTHESIA

5-Jul-2021

Epithelial-mesenchymal transitions create endothelial cells and tumor growth

Cells that have undergone EMT can promote tumor growth and neovascularization either indirectly, by promoting endothelial transdifferentiation of carcinoma cells, or directly, by acquiring an endothelial phenotype, with FOXC2 playing key roles in these processes

PEER-REVIEWED PUBLICATION | /LIFE SCIENCES/CELL BIOLOGY/CELLS/VASCULAR CELLS/ENDOTHELIAL CELLS

5-Jul-2021

Genome wide DNA methylation landscape reveals glioblastoma's influence

These Oncotarget results suggest that GBM might induce epigenetic alterations in tumor infiltrating CD4 T-cells

PEER-REVIEWED PUBLICATION | /HEALTH AND MEDICINE/DISEASES AND DISORDERS/CANCER/BRAIN CANCER/GLIOBLASTOMAS

5-Jul-2021

Loss of CPAP in oral cancer

CPAP also plays a vital role in suppressing tumorigenesis in OSCC by facilitating EGFR homeostasis

PEER-REVIEWED PUBLICATION | /LIFE SCIENCES/PHYSIOLOGY/PATHOPHYSIOLOGY/NEOPLASTIC PROCESSES/TUMORIGENESIS

2-Jul-2021

mTORC1 and PLK1 inhibition in adenocarcinoma NSCLC

All these preclinical data strongly suggest that the inhibition of mTORC1 and PLK1 proteins may be a promising therapeutic approach for NSCLC patients

PEER-REVIEWED PUBLICATION | /LIFE SCIENCES/SIGNAL TRANSDUCTION/SIGNALING PATHWAYS/PI3K PATHWAY

30-Jun-2021

Treatment outcomes in patients with advanced hepatocellular carcinoma

In CTP class A patients, IGF/CTP score B was associated with shorter PFS and OS

PEER-REVIEWED PUBLICATION | /HEALTH AND MEDICINE/DISEASES AND DISORDERS/CANCER/CARCINOMA/HEPATOCELLULAR CARCINOMA

28-Jun-2021

Novel markers of colorectal tumors exhibiting microsatellite instability

By incorporating cell composition into their regression model, they identified 3,193 differentially expressed genes, of which 556 were deemed novel.

PEER-REVIEWED PUBLICATION | /LIFE SCIENCES/GENETICS/HUMAN GENETICS/MEDICAL GENETICS/GENETIC DISORDERS

28-Jun-2021

Predicting clinical outcomes using cancer progression associated signatures

The P142 panel of metrics successfully predicted cancer progression status in patients with some, but not all cancer types analyzed.

PEER-REVIEWED PUBLICATION | /HEALTH AND MEDICINE/MEDICAL SPECIALTIES/ONCOLOGY/CANCER PATIENTS

28-Jun-2021

Glucocorticoid receptor antagonism promotes apoptosis in solid tumor cells

Support recently reported findings of clinical benefit when relacorilant is added to paclitaxel-containing therapy in patients with ovarian and pancreatic cancers and provide a new rationale for combining relacorilant with additional cytotoxic agents.

PEER-REVIEWED PUBLICATION | /LIFE SCIENCES/CELL BIOLOGY/CELLULAR PHYSIOLOGY/CELL DEATH/CELL APOPTOSIS

28-Jun-2021

Prostate cancer and a possible link with schizophrenia

The importance of complex networks of heterotypic interactions between multiple distinct cell types (both malignant and normal) and regulatory circuits has now become widely recognized.

PEER-REVIEWED PUBLICATION | /LIFE SCIENCES/GENETICS/HUMAN GENETICS/MEDICAL GENETICS/GENETIC DISORDERS

11-Jun-2021

Anti-hormonal treatment eligibility in granulosa cell tumors of the ovary

Granulosa cell tumors are a well-defined ovarian cancer subtype, responsible for 2-5% of ovarian malignancies with an annual incidence of 0.6-1.0 per 100.000 women worldwide.

PEER-REVIEWED PUBLICATION | /LIFE SCIENCES/ORGANISMAL BIOLOGY/ANATOMY/TISSUE/NEOPLASMS/OVARIAN TUMORS

9-Jun-2021

The drug sensitivity of hepatocellular cancer cells

'Hepatocellular carcinoma (HCC) is the third leading cause of cancer related death worldwide, with a poor median survival time after diagnosis of six months.'

PEER-REVIEWED PUBLICATION | /HEALTH AND MEDICINE/DISEASES AND DISORDERS/CANCER/CARCINOMA/HEPATOCELLULAR CARCINOMA

7-Jun-2021

Infiltration in human skin squamous-cell carcinoma

Over the last few years, oncology research is increasingly focused on the understanding of mutual interactions between cancer, stromal and immune cells in the tumor microenvironment.

PEER-REVIEWED PUBLICATION | /LIFE SCIENCES/ORGANISMAL BIOLOGY/ANATOMY/TISSUE/NEOPLASMS/SKIN TUMORS

7-Jun-2021

Inflammatory microenvironment & hepatic macrophage in hepatocellular carcinoma

"The incidence of hepatocellular carcinoma (HCC) is increasing worldwide, and HCC is amongst the leading causes of cancer death globally."

PEER-REVIEWED PUBLICATION | /HEALTH AND MEDICINE/DISEASES AND DISORDERS/CANCER/CARCINOMA/HEPATOCELLULAR CARCINOMA

4-Jun-2021

Lung squamous cell carcinoma tumors reveal therapeutic alterations

"Lung cancer is the leading cause of cancer-related deaths across the globe with more than 1.7 million deaths annually."

PEER-REVIEWED PUBLICATION | /LIFE SCIENCES/ORGANISMAL BIOLOGY/ANATOMY/RESPIRATORY SYSTEM/LUNGS

2-Jun-2021

E6-specific inhibitors as therapeutics for HPV+ head and neck carcinomas

"Head and neck squamous cell carcinomas (HNSCC) are heterogeneous tumors that arise in the upper respiratory tract and are the 6th most common cancer worldwide by incidence."

PEER-REVIEWED PUBLICATION | /LIFE SCIENCES/ORGANISMAL BIOLOGY/ANATOMY/NECK

2-Jun-2021

Progression in high-risk non-muscle invasive bladder cancer

This Oncotarget study examined the importance of the De Ritis ratio as a prognostic marker in high-risk NMIBC

PEER-REVIEWED PUBLICATION | /HEALTH AND MEDICINE/MEDICAL SPECIALTIES/PATHOLOGY/DISEASE SUSCEPTIBILITY/RISK FACTORS

31-May-2021

Piperlongumine promotes death of retinoblastoma cancer cells

These Oncotarget findings suggest that PL reduces tumor growth and induces cell death by regulating the cell cycle

PEER-REVIEWED PUBLICATION | /HEALTH AND MEDICINE/DISEASES AND DISORDERS/CANCER/EYE CANCERS/RETINOBLASTOMA

31-May-2021

A ghrelin receptor inverse agonist for positron emission tomography

"The growth hormone secretagogue receptor type 1a (GHS-R1a) is the known biological relevant receptor of the endogenous ligand and pleiotropic hormone Ghrelin (acronym growth hormone release inducing), which mediates a broad range of complex biological functions [1], such as regulation of the body weight, body composition and energy expenditure."

PEER-REVIEWED PUBLICATION | /LIFE SCIENCES/BIOCHEMISTRY/BIOMOLECULES/HORMONES/GROWTH HORMONE

31-May-2021

Activation of plasmacytoid dendritic cells promotes AML-cell fratricide

These Oncotarget findings suggest that the tolerogenic phenotype of pDCs in AML can be reversed

PEER-REVIEWED PUBLICATION | /HEALTH AND MEDICINE/DISEASES AND DISORDERS/CANCER/LEUKEMIA/MYELOID LEUKEMIA

31-May-2021

1B3 supports strong potential for therapeutic intervention in oncology

'Despite decades of research and an unprecedented advancement of therapeutic options [1], cancer accounts for one in every six deaths worldwide, with ~18,000,000 new cases diagnosed in 2018 and expected to grow to ~30,000,000 by 2040.'

PEER-REVIEWED PUBLICATION | /HEALTH AND MEDICINE/CLINICAL MEDICINE/MEDICAL TREATMENTS/CANCER TREATMENTS

31-May-2021

Quantitative proteome profiling stratifies fibroepithelial lesions of the breast

The present Oncotarget work shed light on a brief mechanistic framework of PTs aggressive nature and present potential biomarkers to differentiate overlapping FELs that would be of practical utility in augmenting existing diagnosis and disease management for this rare tumor.

PEER-REVIEWED PUBLICATION | /HEALTH AND MEDICINE/DISEASES AND DISORDERS/CANCER/BREAST CANCER

31-May-2021

STAT3 induces the expression of GLI1 in chronic lymphocytic leukemia cells

Chronic lymphocytic leukemia (CLL) is characterized by gradual accumulation of neoplastic B cells.

PEER-REVIEWED PUBLICATION | /LIFE SCIENCES/CELL BIOLOGY/CELLS/BONE MARROW CELLS/B LYMPHOCYTES

31-May-2021

Creation of a new class of radiosensitizers for glioblastoma

These Oncotarget data reveal a new class of mibefradil-based DNA repair inhibitors which can be further advanced into pre-clinical testing and eventually clinical trials, as potential GBM radiosensitizers.

PEER-REVIEWED PUBLICATION | /HEALTH AND MEDICINE/DISEASES AND DISORDERS/CANCER/BRAIN CANCER/GLIOBLASTOMAS

26-May-2021

The Hippo pathway, RABL6A, and p53-MDM2 axes in sarcomas

Dr. Munir R. Tanas from The University of Iowa said, "Sarcomas are difficult to treat malignant mesenchymal neoplasms arising in bone or soft tissue."

PEER-REVIEWED PUBLICATION | /HEALTH AND MEDICINE/CLINICAL MEDICINE/MEDICAL TREATMENTS/CANCER TREATMENTS

24-May-2021

Urine protein biomarkers of bladder cancer

These Oncotarget findings suggest that urine IL-1α, IL-1ra and IL-8 are useful indicators of bladder cancer.

PEER-REVIEWED PUBLICATION | /LIFE SCIENCES/ORGANISMAL BIOLOGY/ANATOMY/BODY FLUIDS/URINE

24-May-2021

Retaining nanomolar potency in lung cancer with therapy-refractory mutations

The gene correlates of LP-184 sensitivity allow additional personalization of therapeutic options for future treatment of NSCLC.

PEER-REVIEWED PUBLICATION | /HEALTH AND MEDICINE/CLINICAL MEDICINE/MEDICAL TREATMENTS/GENE THERAPY

24-May-2021

The comprehensive genomic profiling test, GEM ExTra®

Proprietary bioinformatics, paired with comprehensive clinical curation results in reporting that defines clinically actionable, FDA-approved, and clinical trial drug options for the management of the patient's cancer.

PEER-REVIEWED PUBLICATION | /HEALTH AND MEDICINE/CLINICAL MEDICINE/MEDICAL DIAGNOSIS/MEDICAL TESTS

20-May-2021

Inhibition of resistant triple-negative breast cancer cells

The Oncotarget author's analyses of protein markers of epithelial-to-mesenchymal transition indicated that treatments with 6-mercaptopurine and/or 5-azacitidine do not significantly reverse this process in their model.

PEER-REVIEWED PUBLICATION | /LIFE SCIENCES/CELL BIOLOGY/CELLS/CANCER CELLS/BREAST CANCER CELLS

19-May-2021

Phase 1 study of Z-Endoxifen in patients with solid tumors

The Oncotarget article provides evidence that antitumor activity and prolonged stable disease are achieved with Z-endoxifen despite prior tamoxifen therapy.

PEER-REVIEWED PUBLICATION | /HEALTH AND MEDICINE/DISEASES AND DISORDERS/CANCER/BREAST CANCER

17-May-2021

Caloric restriction creates a metabolic pattern of chronological aging delay

The Oncotarget authors propose a model of how the specific remodeling of cellular metabolism by caloric restriction contributes to yeast chronological aging delay.

PEER-REVIEWED PUBLICATION | /HEALTH AND MEDICINE/HEALTH CARE/HEALTH COUNSELING/DIETARY COUNSELING/CALORIC RESTRICTION

17-May-2021

CABYR-a/b and CABYR-c hold promise as targets for specific immunotherapy

CABYR expression in tumors was further confirmed by immunohistochemistry

PEER-REVIEWED PUBLICATION | /HEALTH AND MEDICINE/DISEASES AND DISORDERS/CANCER/COLORECTAL CANCER

17-May-2021

Oncotarget receives 2021 Best of Orchard Park Award

Oncotarget has been selected for the 2021 Best of Orchard Park Award in the Publisher category by the Orchard Park Award Program.

GRANT AND AWARD ANNOUNCEMENT | /SOCIAL SCIENCES/ECONOMICS/MACROECONOMICS/MARKET ECONOMICS

26-Apr-2021

Phase 1 study of Z-Endoxifen in patients with solid tumors

The Oncotarget article provides evidence that antitumor activity and prolonged stable disease are achieved with Z-endoxifen despite prior tamoxifen therapy.

PEER-REVIEWED PUBLICATION | /HEALTH AND MEDICINE/DISEASES AND DISORDERS/CANCER/BREAST CANCER

25-Mar-2021

Ibuprofen disrupts protein complex in colorectal cells

The Oncotarget data shed new light on the biochemical mechanisms behind ibuprofen's action on alternative spliced RAC1B and may support its use in personalized approaches to CRC therapy or chemoprevention regimens.

PEER-REVIEWED PUBLICATION | /HEALTH AND MEDICINE/CLINICAL MEDICINE/MEDICAL TREATMENTS/DRUG THERAPY/MEDICATIONS/ANALGESICS

22-Mar-2021

Hispanic Chronic myelomonocytic leukemia patients

This Oncotarget study had significantly lower mutation rates in ASXL1 and SETBP1, and a higher rate of muTET2/wtASXL1

PEER-REVIEWED PUBLICATION | /LIFE SCIENCES/GENETICS/HUMAN GENETICS/MEDICAL GENETICS/CYTOGENETICS

22-Mar-2021

Predictors of immunotherapy benefit in Merkel cell carcinoma

Dr. Glenn J. Hanna from CCR/NCI in Bethesda, MD as well as The Dana-Farber Cancer Institute in Boston Massachusetts said, "Merkel cell carcinoma (MCC) is a relatively rare cancer, with roughly 400 cases per 100,000 persons each year in the United States".

PEER-REVIEWED PUBLICATION | /LIFE SCIENCES/CELL BIOLOGY/CELLS/CANCER CELLS

22-Mar-2021

Quantitative proteome profiling stratifies fibroepithelial lesions of the breast

The present Oncotarget work shed light on a brief mechanistic framework of PTs aggressive nature and present potential biomarkers to differentiate overlapping FELs that would be of practical utility in augmenting existing diagnosis and disease management for this rare tumor.

PEER-REVIEWED PUBLICATION | /HEALTH AND MEDICINE/DISEASES AND DISORDERS/CANCER/BREAST CANCER

18-Mar-2021

Genomic and neoantigen evolution in head and neck squamous cell carcinoma

In this Oncotarget study, the authors characterized the mutational and neoantigen burden between primary and first recurrence tumors in 23 patients with HNSCC.

PEER-REVIEWED PUBLICATION | /LIFE SCIENCES/IMMUNOLOGY/ANTIGENS/NEOANTIGENS

17-Mar-2021

A novel isoform of Homeodomain-interacting protein kinase-2

This @Oncotarget study indicates that HIPK2 isoform 3, the main HIPK2 isoform expressed in NSCLC, promotes YAP/TEAD transcriptional activity in NSCLC cells.

PEER-REVIEWED PUBLICATION | /LIFE SCIENCES/BIOCHEMISTRY/BIOMOLECULES/PROTEINS/ISOFORMS

15-Mar-2021

MicroRNA-4287 is controlling epithelial-to mesenchymal transition in prostate cancer

miR-4287 has potential diagnostic and therapeutic significance in preventing advanced, metastatic disease

PEER-REVIEWED PUBLICATION | /HEALTH AND MEDICINE/DISEASES AND DISORDERS/CANCER/PROSTATE CANCER

15-Mar-2021

Folinic acid in colorectal cancer: Esquire or fellow knight?

Showing a clear clinical benefit for patients, irrespective of RAS mutational status, primitive tumor side and metastases surgery

PEER-REVIEWED PUBLICATION | /LIFE SCIENCES/PHYSIOLOGY/PATHOPHYSIOLOGY/NEOPLASTIC PROCESSES/METASTASIS

15-Mar-2021

Sensitivity testing on ovarian cancer cells isolated from malignant ascites

The aim of this @Oncotarget study is to determine whether tumor cells isolated from ascites of EOC patients can be used to determine chemotherapy sensitivity by using in vitro proliferation assays

PEER-REVIEWED PUBLICATION | /HEALTH AND MEDICINE/CLINICAL MEDICINE/MEDICAL TREATMENTS/CANCER TREATMENTS/CHEMOTHERAPY

8-Mar-2021

High-fat ovariectomized mice susceptible to accelerated tumor growth

There is convincing evidence that excess body weight is associated with increased risk for late onset (> 50 years of age) colorectal cancer (CRC)

PEER-REVIEWED PUBLICATION | /HEALTH AND MEDICINE/DISEASES AND DISORDERS/METABOLIC DISORDERS/OBESITY

8-Mar-2021

Estrogen receptor α polymorphism is associated with dementia

"In conclusion, estrogen receptor α PvuII polymorphism is associated with dementia in a Brazilian cohort"

PEER-REVIEWED PUBLICATION | /SOCIAL SCIENCES/PSYCHOLOGICAL SCIENCE/CLINICAL PSYCHOLOGY/COGNITIVE DISORDERS/DEMENTIA

8-Mar-2021

Identification intermediate-risk subgroups in metastatic clear-cell renal cell carcinoma

"Elevated PLT count seems to identify a subgroup of patients with poor outcome in the IMDC intermediate-risk population with ccRCC"

PEER-REVIEWED PUBLICATION | /HEALTH AND MEDICINE/DISEASES AND DISORDERS/NEPHROPATHIES/KIDNEY CANCER

1-Mar-2021

Exploiting the metabolic dependencies of the broad amino acid transporter SLC6A14

"Suggesting that combined targeting of SLC6A14 and AMPK can be exploited as a therapeutic approach to starve tumor cells"

PEER-REVIEWED PUBLICATION | /LIFE SCIENCES/CELL BIOLOGY/CELLS/NEOPLASTIC CELLS/TUMOR CELLS

1-Mar-2021

Effect of liver fibrosis on survival in patients with intrahepatic cholangiocarcinoma

The @Oncotarget authors aimed to assess the effect of cirrhosis on outcomes in iCCA patients

PEER-REVIEWED PUBLICATION | /HEALTH AND MEDICINE/DISEASES AND DISORDERS/FIBROSIS

1-Mar-2021

Targeting engineered cytokine with interleukin to the neovasculature of tumors

"The results suggest that this product, or similar fusion proteins featuring an N-terminal fusion in the diabody format, may deserve to be investigated in clinical trials"

PEER-REVIEWED PUBLICATION | /LIFE SCIENCES/BIOCHEMISTRY/BIOMOLECULES/PROTEINS/CHIMERIC PROTEINS

22-Feb-2021

MEK inhibitors relevant to SARS-CoV-2 infection

The @Oncotarget authors show a drug class-effect with MEKi to stimulate NK cells, inhibit inflammatory cytokines and block host-factors for SARS-CoV-2 infection leading also to suppression of SARS-CoV-2-S pseudovirus infection of human cells

PEER-REVIEWED PUBLICATION | /HEALTH AND MEDICINE/DISEASES AND DISORDERS/INFECTIOUS DISEASES/MICROBIAL INFECTIONS/VIRAL INFECTIONS/COVID 19

22-Feb-2021

MEK is a promising target in the basal subtype of bladder cancer

"The @Oncotarget authors demonstrate that MEK inhibitors are a promising targeted therapy for the basal subtype of bladder cancer, and their data indicate that drug screening of 3D cultures provides an important resource for hypothesis generation"

PEER-REVIEWED PUBLICATION | /HEALTH AND MEDICINE/CLINICAL MEDICINE/MEDICAL TREATMENTS/CANCER TREATMENTS/CANCER MEDICATION

22-Feb-2021

Hemoglobin increases the effectiveness of chemotherapy in lung cancer

Additional animal studies revealed that co-administration of PolyHb with cisplatin attenuated tumor growth without alleviating hypoxia

PEER-REVIEWED PUBLICATION | /HEALTH AND MEDICINE/DISEASES AND DISORDERS/CANCER/LUNG CANCER

15-Feb-2021

Cancer stem cells and macrophages against cancer

The aim of this Oncotarget review is to define the complex crosstalk between these two cell types and to highlight potential future anti-cancer strategies

PEER-REVIEWED PUBLICATION | /LIFE SCIENCES/CELL BIOLOGY/CELLS/STEM CELLS/CANCER STEM CELLS

15-Feb-2021

AKT isoforms have discrete expression in triple negative breast cancers

Oncotarget recently published "AKT isoforms have discrete expression in triple negative breast cancers and roles in cisplatin sensitivity" which reported that the authors investigated the expression and net effect of the individual isoforms in triple negative breast cancers and response to cisplatin treatment using cellular, mice models and clinical samples.

PEER-REVIEWED PUBLICATION | /LIFE SCIENCES/BIOCHEMISTRY/BIOMOLECULES/PROTEINS/ISOFORMS

15-Feb-2021

Melatonin increases overall survival of prostate cancer patients

'The results of the use of melatonin drugs in palliative treatment of patients with end-stage prostate cancer are shown'

PEER-REVIEWED PUBLICATION | /HEALTH AND MEDICINE/MEDICAL SPECIALTIES/ENDOCRINOLOGY/HORMONES/MELATONIN

10-Feb-2021

Combination of copanlisib with cetuximab improves tumor response

"These data support further investigation of PI3K inhibition in HNSCC and suggests gene expression patterns associated with PI3K signaling"

PEER-REVIEWED PUBLICATION | /LIFE SCIENCES/SIGNAL TRANSDUCTION/SIGNALING PATHWAYS/PI3K PATHWAY

10-Feb-2021

Evaluation of cancer-derived myocardial impairments using a mouse model

'The established mouse cachexia model can therefore be considered useful for analyzing cancer-derived myocardial damage'

PEER-REVIEWED PUBLICATION | /HEALTH AND MEDICINE/MEDICAL SPECIALTIES/ONCOLOGY/CANCER PATIENTS

10-Feb-2021

The goal of geroscience is life extension

Dr. Mikhail V. Blagosklonny from The Roswell Park Cancer Institute said, "Although we do not know everything about aging, we now know enough to start its pharmacologic suppression using clinically approved drugs."

PEER-REVIEWED PUBLICATION | /SOCIAL SCIENCES/DEMOGRAPHY/VITAL STATISTICS/LIFE SPAN

2-Feb-2021

The pro-apoptotic actions of 2-methoxyestradiol against ovarian cancer

The objective of this Oncotarget study was to elucidate the molecular mechanism of actions of 2MeOE2, a known microtubule disrupting agent, in inducing apoptosis in ovarian tumors

PEER-REVIEWED PUBLICATION | /HEALTH AND MEDICINE/DISEASES AND DISORDERS/CANCER/OVARIAN CANCER

1-Feb-2021

Simvastatin is a potential candidate drug in ovarian clear cell carcinomas

"Simvastatin efficiently controlled OCCC proliferation and migration, thus showing potential as a candidate drug for the treatment of OCCC."

PEER-REVIEWED PUBLICATION | /LIFE SCIENCES/BIOCHEMISTRY/BIOMOLECULES/ENZYMES/GTPASES/RHO FAMILY

1-Feb-2021

Neuroendocrine carcinoma of uterine cervix findings shown by MRI

"The Oncotarget author's findings show that MRI is reliable for T staging of cervical NEC"

PEER-REVIEWED PUBLICATION | /HEALTH AND MEDICINE/CLINICAL MEDICINE/MEDICAL DIAGNOSIS/MEDICAL TESTS/MEDICAL IMAGING/MAGNETIC RESONANCE IMAGING

1-Feb-2021

Prognostic biomarker for patients with hepatocellular carcinoma

Reduced expression of TBX15 in tumor tissue represents a potential biomarker for predicting poor survival of patients with HCC

PEER-REVIEWED PUBLICATION | /HEALTH AND MEDICINE/DISEASES AND DISORDERS/CANCER/CARCINOMA/HEPATOCELLULAR CARCINOMA

25-Jan-2021

Improved therapeutic efficacy of unmodified anti-tumor antibodies

The Oncotarget findings suggest that MEKi induced an increased expression of tumor-associated antigens, which in combination with anti-tumor antibodies, generated a robust adaptive anti-tumor response that was sustained by immune checkpoint inhibition therapy.

PEER-REVIEWED PUBLICATION | /LIFE SCIENCES/IMMUNOLOGY/CANCER IMMUNOLOGY/CANCER IMMUNOTHERAPY/ANTIBODY THERAPY

25-Jan-2021

Drug-resistant cells grow exponentially in metastatic prostate cancer

The Oncotarget authors show that the drug-resistant, metastasis-causing cells are capable of producing drug-resistant, exponentially growing tumors, responsible for tumor growth as a patient receives different treatments

PEER-REVIEWED PUBLICATION | /LIFE SCIENCES/PHYSIOLOGY/PATHOPHYSIOLOGY/NEOPLASTIC PROCESSES/METASTASIS

25-Jan-2021

PD-1/PD-L1 expression in anal squamous intraepithelial lesions

Dr. Margot Bucau from The Hôpital Bichat-Claude Bernard said, "Anal intraepithelial neoplasia (AIN) is the precursor lesion for anal squamous cell carcinomas (ASCC).

PEER-REVIEWED PUBLICATION | /HEALTH AND MEDICINE/DISEASES AND DISORDERS/SYMPTOMATOLOGY/LESIONS

11-Jan-2021

Targeted lymphodepletion with a CD45-directed antibody radioconjugate

"Here the Oncotarget authors describe the results of preclinical studies with an anti-mouse CD45 antibody 30F11"

PEER-REVIEWED PUBLICATION | /HEALTH AND MEDICINE/CLINICAL MEDICINE/MEDICAL TREATMENTS/CELL THERAPIES

11-Jan-2021

HIV +/- patients with lymphoma as a predictor of outcome & tumor proliferation

The Oncotarget author's hypothesis is that ADC values will inversely correlate with Ki-67 expression and that tumors with higher ADC values above the median will have improved OS and PFS

PEER-REVIEWED PUBLICATION | /APPLIED SCIENCES AND ENGINEERING/INFORMATION SCIENCE/INFORMATION PROCESSING/DATA VISUALIZATION/HISTOGRAMS

11-Jan-2021

Oncology Press Archive 2020 - 2017